Hematology Week
Susan Hasty, Publisher
Table of Contents . . . December 20th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Hematology Week | Other Publications
Colorectal Cancer - APC gene mutations may play role in origin of sporadic colorectal adenomas
Diagnostics - PCR test differentiates between Staphylococcus aureus and S. intermedius
Natural Killer Cells - NK cell activation enhanced by IL2 in presence of circulating immune complexes
Quality Assurance - Inter-laboratory quality control determined via real-time PCR
Viral Nucleotide Quantitation - rPCR quantitates JC and BK viral genomes rapidly and without radionucleotides
Acute Lymphoblastic Leukemia - Busulfan good alternative to TBI to improve quality of life in childhood ALL
Acute Lymphoblastic Leukemia - DLI successfully treats hematological/extramedullary relapse of MLL-positive ALL
Acute Myeloid Leukemia - Relapse is major cause of treatment failure after BMT in pediatric AML
Acute Myeloid Leukemia - Tailored and targeted therapy possible in pediatric acute myeloid leukemia
Acute Myocardial Infarction - Abciximab does not enhance effect of reteplase on ST-segment elevation
Acute Promyelocytic Leukemia - Novel immunoassay provides rapid and accurate APL diagnosis
Alcohol Abuse - Ferulic acid influences prooxidant antioxidant status
Allergy & Immunology - IL-13 not necessary to maintain airway hyperresponsiveness to allergen-challenge
Antibiotics - Antibiotic use database used for benchmarking and resistance research
Antibiotics - Macrolide antibiotics induce apoptosis of human peripheral lymphocytes
Aplastic Anemia - DRS-1 is candidate autoantigen in AA patients harboring minor group of PNH cells
Apoptosis - Activated NK/CD8+ cells express TRAIL and TRAIL receptors
Apoptosis - Fluorouracil induces apoptosis and surface molecule modulation of PBLs
Apoptosis - Raf/MEK/ERK pathway block sensitizes AML cells to lovastatin-induced apoptosis
Artificial Blood - Glutaraldehyde-linked bovine Hb-based blood substitute increased oxygen affinity
Artificial Lung - Heparin-coated membrane lung shows promise
Atherosclerosis - Forearm vascular function impaired in postmenopausal women with low BMD
Atrial Fibrillation - C-reactive protein correlated with thromboembolic and stroke risk factors
Avian Influenza - H5N1 avian influenza A virus genome sequenced from Thailand poultry outbreak
Biological Markers - Biomarkers may characterize functions of polymorphic DNA repair genotypes
Blood Apheresis - NK suppression related to circulating CD34 cell number during PBPC apheresis
Blood Pressure - Society has established guidelines for self-monitoring of blood pressure at home
Blood Volume - Hamilton Hospital acquires BVA-100 blood-volume analyzer
Cardiac Myocytes - Cx45 is essential for coordinated conduction through early cardiac myocytes
Cardiovascular Disease - Development program initiated for combined MC-1 and angiotensin receptor blocker
Choline Deficiency - Choline deficiency induces time- and dose-dependent increase in ROS
Chronic Lymphocytic Leukemia - GVL-mediated immunotherapy might be effective in CLL with unmutated V-H
Chronic Myelogenous Leukemia - Early prediction of molecular remission by monitoring BCR-ABL transcript levels
Clinical Trials - Company suspends enrollment in phase 3 study of pathogen inactivation system
Colon Cancer - Antibody developed that penetrates mutant p53 colon cancer cells and binds p53
Dengue Virus - Peridomestic mosquito adaptation mediates dengue emergence from progenitor DENV
Diagnostics - A novel assay monitors hepatitis C patients for blood ribavirin levels
Diagnostics - Novel electrophoresis system enables simultaneous nitrate/nitrite assessment
Echocardiography - Dobutamine stress ECG provides incremental data for prediction of mortality
Escherichia Coli - E. coli O157 cluster evaluation does not support epidemiologic association
Esophageal Cancer - XPD 751 Gln/Gln genotype associated with risk of esophageal squamous cell cancer
Finance - Ohio organizations get federal funds for nonembryonic stem-cell research
Foamy Virus - Feline foamy virus Tas protein is a DNA-binding transactivator
Formaldehyde Exposure - No links found between formaldehyde exposure and leukemia
Fungal Infection - Fusarium dimerum infection following SCT successfully treated with voriconazole
Gene Expression - Novel RT-PCR assay quantifies multiple gene expressions in individual cells
Graft-versus-Host Disease - Novel CD8 DE loop peptide analog prevents CD8-mediated graft-versus-host disease
HIV/AIDS & Tuberculosis - TB enhances efficient HIV transmission in lower respiratory tract mucosa
HIV/AIDS Disease Progression - Selenium status associated with increased HIV disease progression in pregnancy
HIV/AIDS Pathogenesis - Complement receptor type 3 increases productive HIV-1 infection of DCs
HIV/AIDS Research - HIV-1 virus-like particles lacking nucleocapsid domain fail to package APOBEC3G
HIV/AIDS Research - Selected AA substitutions in C-terminal region of HIV-1 CA affect virus assembly
HIV/AIDS Research - Viremic HIV-1 infection associated with increased overall NK cell activity
HIV/AIDS Therapy - Multiple factors affect quality of life for male HIV/AIDS patients on HAART
HIV/AIDS Therapy - Novel indole beta-diketo acid derivatives have anti HIV-1 integrase activity
HIV/AIDS-Associated Infection - Fusospirochetosis causes necrotic oral ulcers in HIV-infected patients
HIV/AIDS-Related Pneumocystis - Pneumocystis pneumonia infection is a continuing public health issue
Hematology - Imaging details, pathological differences of red blood cells seen in lupus
Hematology - Novel blood gas sensors combine microdialysis and optical monitoring
Hematology - RARbeta2 expression is diminished in myelofibrosis with myeloid metaplasia
Hematology - Some mutations associated with factor VII deficiency have additive effects
Hematology - Structure of erythrocyte NADH-cytochrome b5 reductase determined
Hematopoiesis - GATA-2 plays two functionally distinct roles during HSC ontogeny
Hemoglobin Purification - Hemolysis conditions influence hemoglobin purification
Hemophilia - Awards made to train clinicians on bleeding disorders care
Hemorrhagic Fever Virus - Evidence of segment reassortment in Crimean-Congo hemorrhagic fever virus
Hepatitis - Study to examine efficacy of hepatitis C treatment in Latinos announced
Hypercalciuria - Monocyte vitamin D receptors elevated in idiopathic hypercalciuria
Immunotherapy - CD62L+ T cells less responsive to alloantigen stimulation than naive T cells
Infection - Plasmodium falciparum-infected erythrocytes bind to fibronectin
Infection - Egg quality assurance programs help reduce Salmonella Enteritidis illness
Influenza - Kriging analysis spots geographic/temporal trends in influenza epidemics
Keratoconjunctivitis - Moraxella bovis isolated from cattle with infectious keratoconjunctivitis
Leukemia - Abstracts on forodesine hydrochloride presented at ASH
Leukemia - FDA panel recommends approval of cancer drug for most common childhood leukemia
Leukemia - Interleukin-3 receptor is a target for antileukemic drugs
Leukemia - PAX5 is specific marker of B-cell ALL
Leukemic Stem Cells - Leukemic stem cells are a novel therapy target
Listeria Monocytogenes - Pasteurization destroys Listeria monocytogenes in peanut and chocolate products
Lymphoma - Simian virus 40 not involved in lymphoma pathogenesis
Microbiology - Microbes modulate IL-6/IL-8/TNF-alpha expression/secretion by oral mucosa cells
Monoclonal Antibody - Anti-CD20 monoclonal antibody effective in therapy-refractory chronic GVHD
Monoclonal Antibody - New anti-idiotype antibody binds rituximab on surface of lymphoma cells
Multiple Myeloma - High-dose chemotherapy relapse is risk factor for treatment-related MM mortality
Myelofibrosis - Risk factors determine survival outcome following ASCT in myelofibrosis patients
Myeloproliferative Disorder - PKC412 effectively treats stem cell myeloproliferative disorder
Neisseria Meningitides - MBL enhances IL-1 beta/IL-10 induction by components of N. meningitides
Neural Stem Cell Research - Sox-2 expressed by neural progenitors and astroglia in adult brain
Non-Hodgkin Lymphoma - Allogeneic BMT increases long-term survival in advanced follicular lymphoma
Non-Hodgkin Lymphoma - Cancer risk appears lower with multiple pregnancies, higher with later menarche
Non-Hodgkin Lymphoma - Company provides update on MyVax Personalized Immunotherapy
Nosocomial Infections - Infection control measures rapidly controlled Norovirus hospital spread
Nutrition - Blood lead concentration, dietary intakes studied in 3-12 month infants
Obstetrics - Heparin used in case of hypertriglycideremia-induced pancreatitis in pregnancy
Outbreak Surveillance - Syndromic surveillance rapidly detects infectious disease outbreaks
Outbreak Surveillance - U.S. approach to outbreak detection uses five interacting health care systems
Personnel - Pharmaceutical company announces senior executive appointments
Physiology - Fibrin stimulates platelets to increase factor VIIIa binding site expression
Physiology - Liver C-JUN N-terminal kinase activated by tissue hypoxia in hemorrhagic shock
Physiology - Regulation of kidney vasodilation and aspartate receptor expression
Platelets - Aspirin and clopidogrel are indicated for patients with acute coronary syndromes
Pneumocystis Pneumonia Transmission - PCP transmitted from hospitalized HIV patients to renal transplant recipients
Reduced-Intensity Stem Cell Transplantation - NCI Common Toxicity Criteria is appropriate in toxicity evaluation of RIST
Renal Artery Stenosis - Severe-thoracic aortic plaque is strongly associated with renal artery stenosis
SARS Prevention - Masks/handwashing effective but gowns/gloves not effective in SARS control
SARS Transmission - Main mode of SARS transmission through droplet spread and close/direct contacts
Salmonella Outbreak - Salmonella enteritidis outbreak associated with school-lunch dessert
Salmonella Outbreaks - S. enterica serotype typhimurium outbreak linked to raw milk consumption
Serum Storage - Long-term serum storage and freeze/thaws show minimal free radical activity
Shellfish Poisoning - Paralytic shellfish poisoning outbreak caused by Gymnodinium catenatum
Shock - Terlipressin can be effective to restore mean arterial pressure in septic shock
Sickle Cell Disease - Sickling impairs microvascular function in murine model
Spermatogenesis - Ghrelin inhibits proliferative activity of immature Leydig cells
Stem Cell Research - Endothelial nitric oxide synthase promotes stem cell mobilization
Stem Cell Research - G-CSF modulates alpha-GalCer-responsive human V alpha 24+ V beta 11+ NKT cells
Stem Cell Research - Growth factors mobilize CXCR4 low/negative primitive HSC from bone marrow
Stem Cell Research - HOXB4 capacity to induce stem cell expansion is DNA-binding dependent
Stem Cell Research - Human hepatocytes formed by human hematopoietic stem cells in sheep
Stem Cell Research - SCF/GM-CSF growth synergism involves kinase-dependent/independent c-Kit activity
Stem Cell Research - Smad2/3 required for expression of genes controlling Nodal signaling
Stem Cell Transplantation - AHSCT favorable for relapsed/refractory acute promyelocytic childhood leukemia
Stem Cell Transplantation - High early toxicities noted in HSCT for immune-mediated diseases
Stroke - Combined estrogen and progesterone doesn't increase stroke risk in rats
Tissue Banking - Arizona legislators look into possible tissue bank laws
Tissue Engineering - Biostability of collagen films controlled for fibroblast cytocompatibility
Tissue Engineering - Biotechnical innovations improving engineering of extracorporal bone tissue
Tissue Engineering - Novel microporous scaffolds use supercritical CO2 for bone tissue engineering
Tissue Engineering - Osteoblast adhesion to common biomaterials regulated through integrin binding
Tissue Engineering - Stromal/mesenchymal cells replaced in recipient following BMT
Tissue Engineering - Thermoreversible hydrogel scaffolds used for articular cartilage engineering
Transplant Medicine - Future selection practices may match specific recipients to specific donors
Transplant Medicine - Liver transplantation and changes in tacrolimus distribution studied
Tumor Necrosis Factor - TRAIL blocks osteoclastic differentiation induced by RANKL + M-CSF
Tumor Suppressor Gene - Decreased ING1 expression indicator of poor prognosis in advanced neuroblastomas
Urinary Bladder Carcinogenesis - Nrf2 essential for efficacy of oltipraz against urinary bladder carcinogenesis
Venous Thromboembolism - Ximelagatran has advantages for prevention of venous thromboembolism
West Nile Virus - High risk of meningoencephalitis in transplant recipients with WNV infection
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