Published in Hematology Week, February 21st, 2005
"This antiapoptotic activity of NF-kappaB involves suppressing the accumulation of reactive oxygen species (ROS) and controlling the activation of the c-Jun N-terminal kinase (JNK) cascade. However, the mechanism(s) by which NF-kappaB inhibits ROS accumulation is unclear."
"We identify ferritin heavy chain (FHC)-the primary iron storage factor-as an essential mediator of the...
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