HIV/AIDS-Associated Dementia
Oxidative stress markers increased in actively progressive HIV dementia
Published in Hematology Week, March 21st, 2005
According to a recent report from the United States, "Oxidative stress leads to the production of reactive oxygen species that can attack lipid membranes resulting in cellular dysfunction and death.
"Cellular redox state is closely linked to ceramide, sphingomyelin, and 4-hydroxynonenal (HNE) levels. We describe data showing increased levels of these oxidative stress markers in HIV encephalitis."
"In addition," said N. Sacktor and coworkers, "actively progressing HIV dementia is associated with increases in HNE and ceramide, while inactive HIV dementia is...
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Source: Hematology Week (2005-03-21)
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