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Nuclear Magnetic Resonance

F-19 NMR is a versatile reporter for non-invasive physiology and pharmacology

Published in Hematology Week, June 13th, 2005

F-19 nuclear magnetic resonance is a versatile reporter for noninvasive physiology and pharmacology.

"The fluorine atom provides an exciting tool for diverse spectroscopic and imaging applications using Magnetic Resonance. The organic chemistry Of fluorine is widely established and it can provide a stable moiety for interrogating many aspects of physiology and pharmacology in vivo.

"Strong NMR signal, minimal background signal and exquisite sensitivity to changes in the microenvironment have been exploited to design and apply diverse reporter molecules," researchers in the United States report.

"Classes of agents are presented to...

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