Susan Hasty, Publisher
Table of Contents . . . August 22nd, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Hematology Week | Other Publications
Lung Cancer - Lung cancer incidence increasing in Sardinia
SARS - Quarantine is cost saving and effective in containing emerging infections
Tuberculosis - High prevalence of tuberculosis among health care workers in Kampala
Tuberculosis - Low sunlight/vegetarian diet cause of vitamin D deficiency in foreigners with TB
Tuberculosis - Targeted screening strategies for pulmonary tuberculosis in prisons unreliable
Adverse Drug Reaction - Advance liver disease hampers tolerance to hepatitis C combination therapy
Alcohol Use - Chronic ethanol consumption may contribute to development of restenosis
Alzheimer Disease - ELISA developed for amino-terminally truncated beta-amyloid peptide quantitation
Anemia - Outcome of clinical analysis of chronic benzene poisoning revealed
Angiology - Children presenting with SoJIA may have coronary artery dilation
Angiology - Coronary retrograde perfusion may be technique for myocardial ischemia
Angiology - Researchers publish new studies and findings in the area of angiology
Angiology - Heat shock proteins analyzed, regulatory role in vascular muscle tone revealed
Angiology - Laser perforation mobilizes matrix graft adaptation in treated arteries
Angiology - Needle-guided ultrasound enhances cannulation success
Angiology - Researchers detail new studies and findings in the area of angiology
Angiology - Skin sterol associated with history of coronary events, published study states
Ischemia - Reports add new data to ischemia research
Antibiotic Resistant Bacteria - Metallo-beta-lactamase-resistant bacteria is an emerging epidemic
Anticancer Drug - Deguelin enhances leukemia cell chemosensitivity with active PI3K/AKT pathway
Antiplatelet Drugs - Alterations of receptor gene may be a mechanism for clopidogrel failure
Antituberculosis Therapy - Some antituberculous drugs alone or in combination enhance PMN functions
Apoptosis - Hsp70 overexpression examined, effect in neonatal brain injury defined
Arteriosclerosis - Long-term treatment with nicorandil may prevent cardiovascular events
Atherosclerosis - Angiogenic growth factors localize in carotid atherosclerotic plaques
Atherosclerosis - Deposition of cholesteryl linoleate results in inflammatory lesions
Atherosclerosis - Higher serum IL-18 levels may be associated with greater carotid IMT
Bartonella - Bartonella causes a broad number of infectious diseases
Benzene Exposure - Occupational exposure to benzene in South Korea
Blood Banking - Controlled-rate freezing used to cryopreserve embryonic stem cells
Blood Clots - Scientists measured elastic moduli of individual fibrin fibers in fibrin clots
Blood Safety - Filtration company awarded long-term contract for leukoreduction filter system
Blood Vessels - Model quantifies spiral motion in vessels, reveals progress of stenosis
Bone Marrow - Predictors of posttraumatic growth after bone marrow transplantation examined
Business & Finance - Cord blood banking company reports strong growth
Business Update - European Union's CHMP adopts positive opinion for NOXAFIL
Business Update - HemoSense strengthens worldwide INRatio System distributor network
C-Reactive Protein - Study examined processing of CRP by human aortic endothelial cells
Cancer Risk Factors - Higher cancer risk found in progeny of mice exposed to X-rays before conception
Cancer Therapy - Deltec and Groshong central venous access port systems compared
Cancer Therapy - Hydrocortisone may play a key role in cancer immunotherapy
Cancer Treatments - PSA quick testing used to screen for prostate cancer
Cardiac Drug Therapy - Insufficient data exist to allow selection of specific inotropic agents
Cardiac Drug Therapy - Study examined cerivastatin/nifedipine in injured coronary arteries
Cardiac Surgery - Hextend and Hespan exhibit same effect on platelet function
Cardiac Therapy - COPD and reversibility should be ascertained before withholding beta-blockers
Cardiogenic Shock - RV dilatation identifies subgroup with an improved long-term prognosis
Cardiology - CRP discriminates poorly between people with/without coronary disease
Cardiology - Cardiac index measures compared during rapid fluid loading
Cardiology - Cardiology must embrace preventive interventions that forestall future events
Cardiology - Device enables the crossing of severe coronary artery stenosis
Cardiology - ECG is the most important diagnostic test for aortic regurgitation
Cardiology - MI patients with high BMI were less likely to have invasive coronary procedures
Cardiology - Model provides method to assess changes in cardiac electrophysiology
Cardiology - Study compares sirolimus-eluting stents with vascular brachytherapy
Cardiology - Study examined recruitable coronary collateral blood ECG changes during PCI
Cardioprotection - Study examined effects of flavonoid treatment on endothelial functions
Cardiopulmonary Bypass - ACT system increased the heparin dose required to exceed target ACT
Cardiovascular Assessment - NIRS provides a valuable method to assess working muscle vasodilation
Cardiovascular Disease - Are there reliable mechanisms relating psychosocial stress to CV diseases?
Cardiovascular Disease - Experimental studies suggest NAD(P)H oxidase activates vascular remodeling
Cardiovascular Disease - Method measures all known plasma forms of vitamins B6 and B2
Cardiovascular Research - 2-methoxyestradiol exerts renal and CV protective effects
Cardiovascular Research - Aerobic exercise increase cardiac function in offspring of HT parents
Cardiovascular Research - Deficiency of eNOS is compensated in coronary circulation, not in aorta
Cardiovascular Research - Study examined autonomic activation in response to stress and anger imagery
Cardiovascular Risk Factors - Specificity of low ankle-brachial index to predict CV outcomes is high
Cardiovascular Risk Factors - Strong associations were found between social class and CV risk factors
Childhood Cancer - Management strategies for asymptomatic cardiac damage discussed
Childhood Cancer - Prevalence of RIB anomalies in normal and childhood cancer patients calculated
Chronic Lymphocytic Leukemia - Trial begins for telomerase inhibitor drug GRN163L in patients with CLL
Cisplatin - Cisplatin, gemcitabine and treosulfan used to treat metastatic uveal melanoma
Clinical Trials - Eight-week doxycycline course safe/effective for lymphatic filariasis
Clinical Trials - Florida hospital approved to enroll patients in phase 2 synthethic blood trial
Clinical Trials - Prasugrel and clopidogrel both resulted in low bleeding rates in PCI patients
Coagulation Therapy - Brand-name and generic warfarin have equivalent performance
Coronary Artery Bypass - Depression and anxiety don't alter CABG candidates' neuropsychology
Coronary Artery Bypass - Depression linked to poor postoperative recovery
Critical Care Medicine - Test to rule out heart attack could reduce hospital admissions
Crohn Disease - MAP specific IS900 DNA is a predominant feature of Crohn disease
Cryptococcus Neoformans - CD8+ T cell function independent of CD4+ T cells in C. neoformans infection
Cytomegalovirus - CMV-specific cytotoxic T cells expanded using recombinant polyepitope
Diagnostics - Contrast-enhancement discerns vessel activity in multiple myeloma images
Diagnostics - Young patients with acute leukemia share unique genetic features
Diet & Nutrition - Effects of diet on blood lipids and energy expenditure examined
Diet & Nutrition - Functional foods may offer stress management benefits
Diet & Nutrition - Olive oil compounds are antioxidants, anti-inflammatories, and antimicrobials
Disease Associations - SARS studied, response of memory CD8+ T cells revealed
Dyslipidemia - Effects of acute coffee ingestion on lipid levels determined
Echocardiography - 3D ECG enables measurement of aortic root in Marfan syndrome
Echocardiography - Ultrasound alters microbubble-based myocardial perfusion assessment
Embryonic Stem Cell Research - Patient-specific ESCs derived from somatic cell nuclear transfer blastocysts
End-Stage Renal Disease - Cortical excitability characterized in different patient populations
Endothelial Cells - Computer-controlled microcirculatory EC culture system devised
Epstein-Barr Virus - SM protein enhances expression of Epstein-Barr virus lytic genes
Escherichia Coli - E. coli 0157:H7 outbreak caused by nonintact blade-tenderized frozen steaks
Escherichia Coli - E. coli alpha-hemolysin studied, structural/functional role of LPS shown
Estrogen - Estrogen elicits cortical zone-specific effects on fetal adrenal gland growth
Familial Hypercholesterolemia - DNA array provides information about mutations and familial hypercholesterolemia
Fibrin Glue - Intralesional injection of Tisseel fibrin glue used for lymphangioma resection
Finance - Genomics-focused pharma reports Q2 loss of $15.7 million
Finance - Laboratory holdings company reports second quarter 2005 financial results
Food Poisoning - Yusho poisoning affected hematogenesis
Gastric Cancer - Serum aberrant methylation compared to conventional tumor markers
Gene Therapy - Enhanced CD20 expression in tumor B cells controlled by ERK-dependent mechanisms
Genital Herpesvirus Infection - Topical microbicides needed for prevention of genital herpes infections
HAM/TSP Pathogenesis - Interferon-beta 1a affects immune mechanisms central to HAM/TSP pathogenesis
HIV/AIDS Coinfection - Neisseria gonorrhoeae enhances infection of dendritic cells by HIV-1
HIV/AIDS Disease Progression Risk Factors - Pattern/type of non-injection drug use associated with progression to AIDS
HIV/AIDS Drug Development - Amino acid Asn136 of HIV-1 RT enables rational design of RT inhibitors
HIV/AIDS Drug Development - Mesuol inhibits HIV-1 replication by targeting NF-kappa B pathway
HIV/AIDS Drug Development - Short hairpin RNAs targeting human cyclin T1 suppresses HIV-1 replication
HIV/AIDS Education - Low health literacy associated with HIV test acceptance
HIV/AIDS Education - Peer education or lecture increases HIV/AIDS knowledge among college students
HIV/AIDS Epidemiology - Differential susceptibility important determinant of steady-state HIV prevalence
HIV/AIDS Epidemiology - Majority of HIV-1 cases among Africa-born patients in Minnesota are non-B
HIV/AIDS Needlestick Injury - Postexposure practice inadequate in medical students with needlestick injury
HIV/AIDS Opportunistic Infection - Calciviruses may be important opportunistic pathogen in HIV-infected children
HIV/AIDS Pathogenesis - CD4+ cells have impaired base excision repair/oxidative base lesion accumulation
HIV/AIDS Pathogenesis - Cultured myeloid dendritic cells from HIV patients fail to differentiate
HIV/AIDS Pathogenesis - HIV Tat induction of IL-10 dysregulation associated with PKR activation
HIV/AIDS Pathogenesis - Infectivity of CXCR4-using isolates depends on CD4 expression
HIV/AIDS Pathogenesis - Peripheral S-phase T cells in HIV disease have a central memory phenotype
HIV/AIDS Pathogenesis - Reports describe recent advances in HIV/AIDS pathogenesis research
HIV/AIDS Perinatal Transmission - Nevirapine resistance after single NVP dose higher in women with HIV-1 subtype C
HIV/AIDS Pharmacokinetics - Body weight/female gender affects enfuvirtide clearance but not safety/efficacy
HIV/AIDS Prevention - HIV prevention program increases willingness to reduce adolescent risk behaviors
HIV/AIDS Prognostic Marker - Early HIV-1 PBMC DNA level predicts disease progression independent of RNA/CD4+
HIV/AIDS Research - Single-chain antibody against HIV-1 external glycoprotein gp120 developed
HIV/AIDS Research - Soluble HIV trimeric Env fragment adopting prefusion gp41 structure developed
HIV/AIDS Risk Behavior - Adults with severe mental illness engage in risky sexual behaviors
HIV/AIDS Risk Behavior - Sexual risk behavior is high among youths in psychiatric care
HIV/AIDS Susceptibility - Screening test may be developed to determine susceptibility to HIV/AIDS
HIV/AIDS Transmission - Incorporation of ABO antigens by HIV-1 may affect viral transmission
HIV/AIDS Treatment Failure - Prevalence of virologic response disappears after 96 weeks on HAART
HIV/AIDS Vaccines - Researchers provide details of new studies and findings in the area of HIV/AIDS vaccines
HIV/AIDS-Related Drug Use - Methadone treatment decreases heroin overdose-related mortality in HIV patients
HIV/AIDS-Related Kaposi Sarcoma - HAART plus liposomal doxorubicin induces tumor remission in HIV-related KS
Health Needs Assessment - Health needs assessment is reliable means of identifying patients' needs
Heart Disease - Response to oral bacteria may be more relevant to HD than periodontic signs
Hematology - Genetically modified natural killer cells overcome HLA-mediated resistance
Hematology - Hematologic follow-up recommended for patients treated with radioiodine
Hematology - Researchers describe findings in hematology studies
Hematopoietic - ESCs grown without embryonic fibroblasts/conditioned media undergo hematopoiesis
Hemolytic Uremia - Streptococcus pneumoniae plus hemolytic uremia is rare in Canada
Hepatic Resection - Novel ultrasound-directed technique used in major hepatic resections
Hepatocellular Carcinoma - Risk factors associated with bile leakage after hepatic resection
Hip Replacement - Aprotinin and EACA treatment reduces post-THA blood loss
Hyperaldosteronism - BK channel dysfunction may underlie forms of hyperaldosteronism
Hyperlipidemia - Clinicians must be aggressive about hyperlipidemia in transplant patients
Hypertension - ACE I/D polymorphism is not useful to predict anti-HT treatment response
Hypertension - Children operated for aortal coarctation have more arterial rigidity
Imaging - Estimation of pulmonary artery pressure by MRI was not feasible
Immunogenetics - Immunoglobulin KV genes isolated by PCR from macaque genomic DNA
Information Technology - Institute for Transfusion Medicine turns to Quovadx for data integration
Intimal Hyperplasia - Patient enrolment in study of therapy to prevent blood vessel blockage complete
Ischemia - Glomerular epithelial cell injury studied, role of ER protein shown
Ischemia - Recent findings illuminate research in ischemia
Kidney Disease - Company reports positive results from DCOR trial favoring use of Renagel
Knee Replacement - Epinephrine-augmented hypotensive epidural anesthesia lowers blood loss
Leptospirosis - Blood monocyte glycolipoprotein studied, Leptospira activation demonstrated
Leukemia - Amino acid concentrations in cerebrospinal fluid measured in ALL children
Leukemia - Children do not show increased susceptibility for developing secondary AML
Leukemia - Fecal fungal flora of immunosuppressed patients studied
Leukemia - Glycated fibrinogen-methotrexate conjugates showed antileukemic activity
Leukemia - Intrathecal chemotherapy evaluated in children with acute leukemia
Leukemia - MLL fusion proteins suppressed p53-mediated response to DNA damage
Liver Transplant - Causes of early acute graft failure elucidated
Lung Transplant - Oxygenation ratio shows promise as early graft dysfunction marker
Lymphoma - MTAP gene silenced by promoter hypermethylation in lymphoma cells
Malaria - P. falciparum malaria occurred in visitors to E. Coast of Dominican Republic
Malaria - Plasmodium falciparum STEVOR peptides studied, RBC binding defined
Malaria - Research in malaria provides new insights
Malaria Vaccine - A. nancymaae is an animal model for malaria subunit vaccine development
Multidrug Resistant - Carbapenem use {{>=}}7 days risks multidrug resistant to P. aeruginosa
Multiple Myeloma - COX-2 is an independent predictor of poor outcome in multiple myeloma
Multiple Myeloma - Cancer-testis antigens correlate with plasma-cell proliferation
Multiple Sclerosis - Modulation of blood vessels is affected by baroreflex dysfunction in MS
Muscular Dystrophy - Muscle side population cells reveal myogenic potential
Mycobacterium Avium - High-temperature/short-time pasteurization inactivates M. avium in milk
Mycobacterium Kansasii - High phenotypic variability of M. kansassi may complicate identification
Mycobacterium Tuberculosis - Early treatment improves MTB-induced disseminated intravascular coagulation
Mycobacterium Tuberculosis - Inducible promoter generates conditional Mycobacerium tuberculosis auxotroph
Mycobacterium Tuberculosis - Pyrosequencing assay rapidly detects rifampin-resistant M. tuberculosis
Mycobacterium Tuberculosis - Virulence of MTB isolates dependent on phenolic glycolipid produced by bacilli
Myeloma - Case of reactive plasmacytosis mimicking multiple myeloma found in pSS patient
Myocardial Infarction - NT-proBNP and renin are predictors of MI risk after stroke or ischemic attack
Neuroscience - New findings in the area of neuroscience described
Neurotransmitters - Blood-retinal barrier studied, nature of Leu transport defined
Norovirus - Multiplex real time RT-PCR assay quantitates norovirus genogroups I and II
Nosocomial Infections - Molecular epidemiology traces hepatitis C outbreaks in a hemodialysis unit
Oncology - Recent findings illuminate research in oncology
Otorhinolaryngology - Use of anterolateral thigh flaps to reconstruct head and neck defects evaluated
Pamidronate - Pamidronate and 1,24(S)-dihydroxyvitamin D-2 inhibited growth of cancer cells
Pancreatic Ductal Carcinoma - Factors predicting recurrence after pancreatic ductal carcinoma resection listed
Patents - Company receives notice of allowance for key U.S. EVLT patent
Pediatric Cardiac Surgery - Surgery for aortic coarctation has excellent results in children under 1 yr. old
Percutaneous Coronary Intervention - PCI with drug-eluting stents highly cost-effective in Germany
Pneumonia - C. pneumoniae kills cells by a caspase-independent pathway
Prognostics - CT scans predicted weight of Wilms tumor
Prostate Cancer - AMACR expression altered in prostatic adenocarcinoma following hormone therapy
Pulmonary Arterial Hypertension - Increased ADMA plasma levels are associated with poor outcome in IPAH
Pulmonary Hypertension - Assessment of cardiopulmonary function reviewed
Radiation Therapy - Risk of CV mortality after irradiation for childhood cancer is increased
Renal Cell Cancer - Renal cell carcinoma reported secondary to tuberculous nephritis
Respiratory Distress Syndrome - Nitric oxide added to CPAP treatment improves oxygenation
SARS - Anti-SARS-coronavirus drugs are crucial for control of future outbreaks
SARS - Protective mask usefulness during SARS outbreak varies among healthcare workers
Smallpox Vaccine - Stable/effective smallpox vaccine constructed from highly attenuated vaccinia
Statins - Rosuvastatin may be an option for patients requiring 50% LDL reduction
Stem Cell Research - BMSCs have limited plasticity to transdifferentiate into cardiac cells in vitro
Stem Cell Research - Dopamine specifically inhibits forebrain neural stem cell proliferation
Stem Cell Research - Postnatal muscle-derived stem cells have extra capacity for self-renewal
Stem Cell Research - Provider of stem cell transplantation, therapy passes 200 cord blood transplants
Stem Cell Research - TGF-beta 1 tightly regulates intestinal mast cell growth/phenotype/function
Stem Cell Research - TGF-beta-1-2-3 & IFN-beta induce hepatocyte growth factor secretion by microglia
Stem Cell Transplantation - CD133+ SCs used for haploidentically mismatched peripheral blood SCT
Stem Cell Transplantation - Fibrinolytic test findings may facilitate early VOD diagnosis in pediatric HSCT
Stem Cell Transplantation - HLH patients with NK-cell deficiency type 3 will probably require SCT to survive
Stem Cell Transplantation - High-dose cyclophosphamide effective for refractory MM after SCT relapse
Stem Cell Transplantation - Mesenchymal stem cell transplants can improve heart function
Stem Cell Transplantation - Most HLH patients using matched related or unrelated donor survive SCT
Stem Cell Transplantation - New research in the area of stem cell transplantation detailed
Stem Cell Transplantation - Nonmyeloablative SCT corrects disease phenotype in leukocyte adhesion deficiency
Stem Cell Transplantation - Reduced-intensity SCT successful in malignant lymphoma/ileostomy patient
Stroke - Atherosclerosis and cervical artery dissection are not well examined
Stroke - Study analyzed outcomes of stroke patients requiring ventilation
Stroke - Study examined predictors of reocclusion in stroke patients treated with tPA
Stroke - Transthoracic ECG should be performed for all stroke patients in sinus rhythm
Systemic Lupus Erythematosus - First patient treated in pivotal phase III lupus nephritis study
Thalassemia - Single-tube osmotic fragility test suitable for diagnosis
Tissue Engineering - Autologous blood vessels engineered from human cells
Tissue Engineering - BMP-2 induces chondrocyte-specific gene expression in synovium-derived SCs
Tissue Engineering - Cultured porcine cartilage pellets used to study rheumatoid arthritis
Tissue Engineering - Tissue engineering for airway reconstruction avoids tracheotomy
Tissue Engineering - Tissue-engineered vascular autografts seeded with autologous bone marrow cells
Toxoplasma Gondii - Stage-specificity of SRS Ags determines immunogenicity in T. gondi infection
Tuberculosis - Beijing genotype is a major cause of drug-resistant tuberculosis in Kazakhstan
Tuberculosis - Differential regulation of local immune response crucial for containment of MTB
Tuberculosis - ELISA more sensitive than immunoblotting for detection of tuberculosis antibody
Tuberculosis - Short-course chemotherapy safe/effective in pediatric respiratory tuberculosis
Tuberculosis - Tuberculosis drugs not handled properly in lower southern Thailand
Tuberculosis - Tuberculosis risk patterns determined for recent immigrants to Ontario
Tuberculous Meningitis - Isoniazid + rifampicin resistance strongly predictive of death in TB meningitis
Type 1 Diabetes - Pancreatic islet transplantation stabilizes diabetes-related pathologies
Urology - Preoperative chlormadinone reduces blood loss during prostate surgery
Vascular Disease - Heritable deficiency of antioxidant enzymes favors ROS accumulation
Vasculitis - Persisting endothelial dysfunction in vasculitis may have consequences
Venous Leg Ulcer - Low-level laser therapy doesn't enhance wound healing
West Nile Fever - WNF encephalitis may present with functional/intellectual impairment in elderly
Yersinia - MAPK/NF-kappa B inhibition needed for rapid apoptosis in infected cells
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