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Cisplatin

Efficacy and safety of intravenous topotecan combinatory chemotherapy tested

Published in Hematology Week, September 19th, 2005

Scientists examined the efficacy and safety of intravenous topotecan in combination with either cisplatin or etoposide.

In a recent article published in the journal Lung Cancer, scientists in France reported, "This phase II study investigated the efficacy and safety of topotecan in combination with either cisplatin or etoposide in untreated extensive disease SCLC (ED SCLC). Patients with untreated ED SCLC were randomized to treatment with T/C (topotecan 1.25 mg/(m2 day) IV days 1-5, cisplatin 50 mg/m2 IV day 5; 41 patients) or T/E (topotecan .75 mg/(m2 day) IV days 1-5, etoposide 60 mg/(m2day) IV days 1-5; 41 patients)...

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