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Stem Cell Research

G-CSF enhances bone marrow stem cell mobilization during acute myocardial infarction

Published in Hematology Week, November 14th, 2005

Granulocyte-colony stimulating factor enhances bone marrow stem cell mobilization during acute myocardial infarction.

According to recent research from Italy, "There is increasing evidence that stem cell (SC) mobilization to the heart and their differentiation into cardiac cells is a naturally occurring process.

"We sought to assess the safety and feasibility of granulocyte-colony stimulating factor (G-CSF) administration in humans to enhance SC mobilization and left ventricle (LV) injury repair during myocardial infarction (MI)."

"Twenty patients with STEMI (mean age, 61±10 years), of whom 14 were submitted to primary...

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