Colon Cancer
Aberrant cytochrome c oxidase subunit I expression is biomarker for increased colon cancer risk
Published in Hematology Week, November 21st, 2005
According to recent research from the United States, "There is an increasing demand for the development of intermediate biomarkers to assess colon cancer risk. We previously determined that a live cell bioassay, which assesses apoptosis resistance in the nonneoplastic colonic mucosa, detects similar to 50% of patients with colon cancer.
"A hypothesis-driven biomarker that reflects apoptosis resistance in routine formalin-fixed, paraffin-embedded tissue would be easier to use. Cytochrome c oxidase is a critical enzyme that controls mitochondrial...
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Source: Hematology Week (2005-11-21)
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