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Leukemia & Crohn Disease

Juvenile myelomonocytic leukemia diagnosed in a child with Crohn disease

Published in Hematology Week, July 31st, 2006

Juvenile myelomonocytic leukemia was diagnosed in a child with Crohn disease.

According to recent research from the United States, "Intestinal adenocarcinoma is a well-known complication of inflammatory bowel disease. Hematologic malignancies, most commonly lymphoma or acute myeloid leukemia, represent a much less well-recognized complication of these disorders; these typically occur in adults with ulcerative colitis."

"We report a fatal case of juvenile myelomonocytic leukemia associated with monosomy 7 in a young child with a clinical history of Crohn disease. Neither the leukemia nor the cytogenetic aberration has been previously reported in a...

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