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Prion Transmission

Prion diagnostic and removal strategies may help control spread via blood transfusion

Published in Hematology Week, July 31st, 2006

Prion diagnostic and removal strategies may help control the risk of prion spread through blood transfusions.

"Prion infections lead to invariably fatal diseases of the CNS, including Creutzfeldt-Jakob disease (CJD) in humans, bovine spongiform encephalopathy (BSE), and scrapie in sheep.

"There have been hundreds of instances in which prions have been transmitted iatrogenically among humans, usually through neurosurgical procedures or administration or pituitary tissue extracts," scientists in Switzerland report.

According to A. Aguzzi and colleagues at the University Hospital of Zurich, "Prions have not generally been regarded as...

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