Hematology
Alternatively spliced tissue factor is a previously unknown piece in the puzzle of hemostasis
Published in Hematology Week, September 4th, 2006
A new review from Germany notes, "Alternatively spliced tissue factor (asTF) has recently been discovered as a soluble form of tissue factor (TF), which circulates in blood and exhibits procoagulant activity. This soluble TF variant expanded the concept of circulating TF by a further element. Up to 30% of the TF antigen found in circulating blood was proposed to be derived from alternative splicing."
"We showed that cytokines induced the expression of asTF and the release from endothelial cells," wrote B....
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Source: Hematology Week (2006-09-04)
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