Bone Marrow Transplantation

Veto cells may be used for tolerance induction without graft-versus-host disease

Published in Hematology Week, October 9th, 2006

Veto cells may be used for tolerance induction without graft-versus host disease in bone marrow transplantation.

In a recently published report, investigators in Israel summarized and updated "new data on the role of veto cells in bone marrow transplantation.

"Studies in mice and humans demonstrate that transplantation of hematopoietic progenitors in numbers larger than commonly used ('megadose' transplants) overcomes major genetic barriers.

"In vitro studies suggest that veto cells, within the population of hematopoietic progenitors, facilitate this favorable outcome. Tolerance induction can be further enhanced by other veto...

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Source: Hematology Week (2006-10-09)

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