Genetics & Genomics

Baseline CRP levels and genetic variation in 9 innate immunity genes show no association

Published in Hematology Week, October 9th, 2006

Baseline C-reactive protein levels and genetic variation in 9 innate immunity genes show no association.

Researchers in the United States report, "It is well-known that baseline levels of C-reactive protein (CRP) are an independent cardiovascular risk factor. We hypothesized that genetic variation with significant influence on CRP levels might be found in genes of the innate immunity system."

"We performed a candidate gene association study examining common single nucleotide polymorphisms in 9 innate immunity genes (CARD15, IRAK1, IRAK4, LBP, LY86, MEFV, TLR2, TLR4 and NFKB1) in relation to CRP levels," explained P. Kozlowski and colleagues at...

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Source: Hematology Week (2006-10-09)

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