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Thrombocytopenic Purpura

Trial data show Promacta lowers bleeding, raises platelet count in thrombocytopenic purpura

Published in Hematology Week, January 8th, 2007

GlaxoSmithKline (GSK) announced additional results from an international phase 2 short-term, 6-week study of its investigational nonpeptide oral platelet growth factor, Promacta (eltrombopag).

Analysis of data from this study showed that Promacta at 50 mg or 75 mg resulted in a positive trend in decrease in bleeding incidence (all grades) in adult patients with chronic idiopathic thrombocytopenic purpura (ITP), an autoimmune condition which results in low blood platelet counts and bleeding from the small blood vessels. These data were presented at the 48th Annual American Society of Hematology (ASH) meeting in Orlando, Florida.

The primary efficacy...

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