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Hematology Week

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Bone Marrow



Researchers from University of Pittsburgh, Department of Surgery discuss findings in bone marrow



April 16th, 2007

New research, "Allopeptide-pulsed dendritic cells and composite tissue allograft survival," is the subject of a report. "Composite tissue allografts (CTAs) contain their own reservoir of vascularized bone marrow, offering novel aspects for the induction of donor-specific tolerance. Additionally, the manipulation of recipient dendritic cells, pulsed with donor allopeptide, has been shown to engender solid organ allograft survival," scientists writing in the journal Microsurgery report.

"To exploit these modalities, we have developed a protocol utilizing injection of recipient bone marrow-derived dendritic cells (BMDCs) pulsed with a donor-derived peptide for use...


Source: Hematology Week (2007-04-16)

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