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Hematology Week

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Hepatocellular Cancer



Research from Okayama University has provided new information about hepatocellular cancer



April 16th, 2007

New research, "Des-gamma-carboxyl prothrombin-promoted vascular endothelial cell proliferation and migration," is the subject of a report. "Des-gamma-carboxyl prothrombin (DCP) is a well recognized tumor marker for hepatocellular carcinoma. Previously, we have demonstrated that DCP stimulates cell proliferation in hepatocellular carcinoma cell lines through Met-Janus kinase 1 signal transducer and activator of transcription 3 signaling pathway," scientists in Okayama, Japan report.

"In the present study, we demonstrated that DCP induces both cell proliferation and migration in human umbilical vein endothelial cells. DCP was found to bind with the kinase insert domain...


Source: Hematology Week (2007-04-16)

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