Thrombosis Risk Factors

Researchers' work from Leiden University focuses on thrombosis risk factors

Published in Hematology Week, August 13th, 2007

Fresh data on thrombosis are presented in the report "Past and future of genetic research in thrombosis." According to recent research from Leiden, Netherlands, "Genetic studies in thrombosis started with coining of the term thrombophilia by Jordan and Nandorff in 1956. Next, antithrombin deficiency was identified in 1965 as a simple genetic entity that increased thrombotic risk, albeit in a small subset of patients."

"This subset was enlarged when, in the 1980s, family studies showed that deficiency of protein C (PC) or its co-factor protein S (PS) increased thrombotic risk. Ten years later activated PC resistance and the underlying genetic trait of factor V Leiden...

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Source: Hematology Week (2007-08-13)

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