Apoptosis Therapy
Research from Tianjin Medical University, Department of Hematology broadens understanding of apoptosis therapy
Published in Hematology Week, August 20th, 2007
Researchers detail in "Simultaneous suppression of multidrug resistance and antiapoptotic cellular defense induces apoptosis in chemoresistant human acute myeloid leukemia cells," new data in apoptosis. "The emergence of acquired drug resistance is a major hurdle in the successful treatment of leukemia. Researches indicated that the main mechanisms of most cancers included so-called "pump" and "nonpump" resistance," scientists in Tianjin, People's Republic of China report.
"We studied the mechanisms involved in the drug resistance of HL-60/ADR and found that its drug resistance was associated with the simultaneous overexpression of XIAP and MRP. We compared the reversal...
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Source: Hematology Week (2007-08-20)
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