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B-Cell Lymphoma

Research on B-cell lymphoma detailed by scientists at University Pierre et Marie Curie (Paris VI)

Published in Hematology Week, October 15th, 2007

Current study results from the report, 'Critical role of monocytes to support normal B cell and diffuse large B cell lymphoma survival and proliferation,' have been published. "Large B cell lymphomas can comprise numerous CD14+ cells in the tumor stroma, which raises the question of whether monocytes can support B cell survival and proliferation. We show that the coculture of monocytes with B cells from peripheral blood or from diffuse large B cell lymphoma enabled prolonged B cell survival," researchers in Paris, France report.

"Under these conditions, diffuse large lymphoma B cells proliferated, and addition of B cell-activating factor of the TNF family (BAFF) and...

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