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Apoptosis Cell Biology

Research results from Institute of Biomedicine update knowledge of apoptosis cell biology

Published in Hematology Week, December 3rd, 2007

New research, 'The proteasome and intracellular redox status: implications for apoptotic regulation in lens epithelial cells,' is the subject of a report. According to recent research from Goteborg, Sweden, "This study aimed to investigate redox regulation of the proteasome as well as the effect of proteasome inhibition on intracellular oxidative status and apoptosis Oxidative stress was induced in cultured human lens epithelial cells (HLECs) and intact mouse lenses by 100 microM H2 O2 . HLECs were also exposed to the reduced and the oxidized forms of glutathione (GSH/GSSG) and the reducing agent dithiotreitol (DTT)."

"The chymotrypsin-like, the...

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