Graft-Versus-Host Disease

Studies from Medical College of Wisconsin, Medical College further understanding of graft-versus-host disease

Published in Hematology Week, February 4th, 2008

According to a study from the United States, "Few studies have tested the benefits of using peripheral blood stem cell (PBSC) grafts versus bone marrow (BM) grafts for unrelated donor transplantation. Yet there has been a substantial change in clinical practice, with increasing numbers of adults receiving unrelated donor PBSC grafts."

"We compared outcomes after 331 PBSC and 586 BM transplants in adults with leukemia and myelodysplastic syndrome (MDS) who were followed for a median of 3 years after transplantation. PBSC recipients were less likely to have chronic myelogenous leukemia (CML) and more likely to have MDS, to have poor performance scores, and to be...

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Source: Hematology Week (2008-02-04)

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