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Hepatitis C Virus Therapy

Study results from National Institutes of Health, Department of Transfusion Medicine provide new insights into hepatitis C virus therapy

Published in Hematology Week, July 14th, 2008

Scientists discuss in 'Sequence uniqueness and sequence variability as modulating factors of human anti-HCV humoral immune response' new findings in hepatitis C virus. "We recently compared the HCV polyprotein to the human proteome in order to test whether amino acid sequences unique to the virus could represent immunodominant epitopic determinants of the human humoral immune response against HCV. We identified a relatively limited number of HCV fragments with no/low similarity to the human host that represented exclusive HCV motifs," scientists writing in the journal Cancer Immunology, Immunotherapy report.

"In this study, the peptides corresponding to low/zero...

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