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Tissue Engineering

Study results from Miami University provide new insights into tissue engineering

Published in Hematology Week, November 10th, 2008

"During insect myogenesis, myoblasts are organized into it pre-pattern by specialized organizer cells. In the Drosophila embryo, these cells have been termed founder Cells and play important roles in specifying muscle identity and in serving as targets for myoblast fusion," scientists in the United States report.

"A group of adult muscles, the dorsal longitudinal (flight) muscles, DLMs, is patterned by persistent larval scaffolds: the second set, the dorsal-Ventral muscles, DVMS is patterned by mono-nucleate founder cells (FCs) that are much larger than the S surrounding myoblasts. Both types of organizer cells express Dumbfounded, which is known to regulate fusion...

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