Published in Hematology Week, November 10th, 2008
"JCV encodes for TAg and has been implicated in colorectal carcinogenesis. We hypothesized that the use of immunosuppression in LTRs facilitates activation of JCV and is responsible for the increased risk of neoplasia. JCV TAg DNA and protein expression were determined in normal colonic epithelium (n=15) and adenomatous polyps (n=26) from LTRs and compared...
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