Published in Hematology Week, February 9th, 2009
"A GVMGFO motif in fibrillar collagens (0 denotes 4-hydroxyproline) binds 3 unrelated proteins: von Willebrand factor (VWF), discoidin domain receptor 2 (DDR2), and the extracellular matrix protein SPARC/osteonectin/BM-40. We report the crystal structure at 3.2 angstrom resolution of human SPARC bound to a triple-helical 33-residue peptide harboring the promiscuous GVMGFO...
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