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Fusion Proteins

Research on fusion proteins published by scientists at Hokkaido University, Institute for Genetic Medicine

Published in Hematology Week, March 9th, 2009

New investigation results, 'Fusion protein consisting of the first immunoglobulin-like domain of porcine nectin-1 and Fc portion of human IgG1 provides a marked resistance against pseudorabies virus infection to transgenic mice,' are detailed in a study published in Microbiology and Immunology. According to recent research from Sapporo, Japan, "Nectin-1 is a Ca2+-independent Ig-like cell-cell adhesion molecule and an alphaherpesvirus receptor that binds to virion glycoprotein D by the first Ig-like domain. We have investigated the antiviral potentials of soluble forms of porcine nectin-1 to PRV infection by generating transgenic mice expressing different types of fusion...

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