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Study findings from University of Illinois provide new insights into life sciences

Published in Hematology Week, March 9th, 2009

Current study results from the report, 'Sex-specific roles of beta-catenin in mouse gonadal development,' have been published. "Sexually dimorphic development of the gonads is controlled by positive and negative regulators produced by somatic cells. Many Wnt ligands, including ones that signal via the canonical beta-catenin pathway, are expressed in fetal gonads. beta-catenin, a key transcriptional regulator of the canonical Wnt pathway and an element of the cell adhesion complex, is essential for various aspects of embryogenesis," scientists writing in the journal Human Molecular Genetics report.

"To study the involvement of beta-catenin in sex determination, we...

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