Hematopoiesis
Study data from Western Michigan University update understanding of hematopoiesis
Published in Hematology Week, July 27th, 2009
"Vertebrate hematopoiesis first produces primitive (embryonic) lineages and ultimately generates the definitive (adult) blood. Whereas definitive hematopoiesis may produce many diverse blood types via a common multipotent progenitor, primitive hematopoiesis has been thought to produce only erythrocytes or macrophages via progenitors that are unipotent for single blood lineages," scientists writing in the journal Developmental Cell report.
"Using a variety of in vivo cell-tracing techniques, we show that primitive blood in zebrafish derives from two different progenitor types. On the dorsal gastrula, blood progenitors are unipotential cells that divide...
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Source: Hematology Week (2009-07-27)
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