Uveitis

Study results from University of Aberdeen in the area of uveitis published

Published in Hematology Week, November 2nd, 2009

According to recent research published in the journal Investigative Ophthalmology & Visual Science, "Macrophages are major contributors to the damage occurring in the retina in experimental autoimmune uveitis (EAU). CCR2 may be needed for efficient recruitment of monocytes to an inflammatory site, and the aim of this study was to determine whether this was the case in EAU."

"EAU was induced and graded in C57BL/6J and CCR2(-/-) mice. Macrophage infiltration and CCR2 expression were assessed using immunohistochemistry. Retinas were examined for MCP-1 expression using RT-PCR. Rolling and infiltration of labeled bone marrow monocytes at the inflamed retinal...

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Source: Hematology Week (2009-11-02)

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