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Acute Promyelocytic Leukemia
Studies from University of Ulm describe new findings in acute promyelocytic leukemia
November 9th, 2009
"Migration of cells is important for tissue maintenance, immune response, and often altered in disease. While biochemical aspects, including cell adhesion, have been studied in detail, much less is known about the role of the mechanical properties of cells," scientists in Ulm, Germany report. "Previous measurement methods rely on contact with artificial surfaces, which can convolute the results. Here, we used a non-contact, microfluidic optical stretcher to study cell mechanics, isolated from other parameters, in the context of tissue infiltration by acute promyelocytic leukemia (APL) cells, which occurs during differentiation therapy with retinoic acid. Compliance...
Source: Hematology Week (2009-11-09)
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