Bacterial Meningitis

Recent studies by R.M.G. Berg and co-authors add new data to bacterial meningitis findings

Published in Hematology Week, November 9th, 2009

"The underlying mechanisms for cerebral blood flow (CBF) abnormalities in acute bacterial meningitis (ABM) are largely unknown. Putative mediators include vasoactive peptides, e. g. calcitonin-gene related peptide (CGRP), vasoactive intestinal peptide (VIP), and endothelin-1 (ET-1), all of which may be affected by therapeutic interventions used in the intensive care unit," investigators in Copenhagen, Denmark report.

"We measured arterial levels as well as the net cerebral flux of these peptides in patients with ABM, and in healthy volunteers undergoing interventions relevant to intensive care. Seven patients with severe ABM and sepsis and fifteen healthy volunteers...

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Source: Hematology Week (2009-11-09)

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