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University of Maryland Medical Center

New class of molecules may help prevent fatal complication in patients with kidney disease

Published in Hematology Week, November 16th, 2009

Researchers at the University of Maryland School of Medicine have made an important discovery about why potassium builds up to dangerous levels in the bloodstream, a relatively common medical problem that affects about eight percent of hospitalized patients. They have identified a new molecular pathway and a new class of molecules responsible for preventing potassium from being excreted normally through the kidney. Their study was just published in the Journal of Clinical Investigation.

The researchers hope that their discovery will lead to the development of a new class of drugs to treat the condition, known as hyperkalemia, which is caused when patients can't properly...

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