Stowers Institute for Medical Research
Linheng Li proposes novel theory for mammalian stem cell regulation
Published in Hematology Week, February 15th, 2010
Linheng Li, Ph.D., Investigator, together with Hans Clevers, M.D., Ph.D., Director of the Hubrecht Institute in Utrecht, Netherlands, co-authored a prospective review published by the journal Science that proposes a model of mammalian adult stem cell regulation that may explain how the coexistence of two disparate stem cell states regulates both stem cell maintenance and simultaneously supports rapid tissue regeneration.
Adult stem cells are crucial for physiological tissue renewal and regeneration following injury. Current models assume the existence of a single quiescent (resting) population of stem cells residing in a single niche of a given tissue.
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Source: Hematology Week (2010-02-15)
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