Published in Hematology Week, February 15th, 2010
"Plasma S100 (S100B) proteins increase in sepsis. S100B is present not only in the brain but also in other tissues. The source of this protein has not been investigated in sepsis. Our aim in this study was to determine whether the brain is an important source of S100B in an experimental sepsis model. Twenty-seven pigs were anesthetized and randomized to either infusion of endotoxin at the rate of 1 mu g.kg(-1).h(-1) (n = 19) or saline (n = 8). Catheters were inserted into a...
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