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Bone Substitutes

Research from University Hospital yields new findings on bone substitutes

Published in Hematology Week, March 22nd, 2010

Research findings, 'Epidermal growth factor (EGF) transfection of human bone marrow stromal cells in bone tissue engineering,' are discussed in a new report. "A novel therapeutic approach for the treatment of bone defects is gene therapy assisted bone tissue engineering using bone marrow stromal cells (hBMSC). The aim of this study was to investigate the influence of human epidermal growth factor (hEGF) on proliferation and alkaline phosphatase (AP) activity of primary hBMSC in vitro. hBMSC cultures were achieved by explantation culture of bone chips," researchers in Munich, Germany report.

"Following exposure to 0-10 ng recombinant hEGF (rhEGF)/ml cell numbers were...

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