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Pharmacyclics, Inc.

Pharmacyclics Announces Multiple Presentations at the American Association for Cancer Research Annual Meeting

Published in Hematology Week, April 26th, 2010

Pharmacyclics, Inc. (NASDAQ:PCYC) announced multiple presentations covering its Btk and HDAC programs at the American Association for Cancer Research (AACR) 2010 Annual Meeting being held April 17-21 in Washington, DC.

The oral presentation describes efficacy of the company's first-in-human Btk inhibitor PCI-32765 in a mouse model of pancreatic cancer (Soucek et al). Two other presentations describe the discovery of drug synergy with the company's HDAC inhibitor, PCI-24781 and the drug bortezomib in neuroblastoma (Currier et al), or with inhibitors of LSD1 in glioblastoma (Singh et al). An additional presentation describes preclinical development of the company's novel...

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