Life Sciences
Report summarizes life sciences study findings from University of Saskatchewan
Published in Hematology Week, May 3rd, 2010
"Various 2-benzylidene-6-(nitrobenzylidene)cyclohexanones were prepared as candidate cytotoxins in which the nitro group was located in the ortho, meta and para positions leading to series 1-3, respectively. The CC50 values towards human HSC-2 and HSC-4 oral squamous cell carcinomas as well as human HL-60 promyelocytic leukemic cells are in the low micromolar range in general," scientists writing in the journal Bioorganic & Medicinal Chemistry report.
"On the other hand, most of the compounds afforded clear evidence of being far less toxic towards human HGF gingival fibroblasts, HPC pulp cells and HPLF periodontal ligament. broblasts which are non-malignant...
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Source: Hematology Week (2010-05-03)
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