HIV/AIDS
Research from Hospital for Sick Children provide new insights into HIV/AIDS
Published in Hematology Week, May 3rd, 2010
Researchers detail in 'Globotriaosyl ceramide receptor function - where membrane structure and pathology intersect,' new data in HIV/AIDS. According to recent research from Toronto, Canada, "The glycosphingolipid globotriaosyl ceramide, (Galalpha1-4Galss1-4 glucosyl ceramide-Gb(3)) also known as CD77 and the P(k) blood group antigen, is bound by both verotoxins and by the HIV adhesin, gp120. Gb(3) plays an important receptor role in VT induced hemolytic uremic syndrome (HUS) and HIV infection."
"The organization of glycolipids, including Gb(3), into lipid rafts is central to both pathologies. The fatty acid heterogeneity within the Gb(3) lipid moiety plays a central...
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Source: Hematology Week (2010-05-03)
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