Apoptosis
Research reports on apoptosis from B.T. Moorthy and colleagues provide new insights
Published in Hematology Week, November 29th, 2010
2010 NOV 29 -- According to recent research from Coimbatore, India, "We have designed and synthesized three novel compounds, 5-isopropylidiene derivatives of 3-dimethyl-2-thio-hydantoin (ITH-1), 3-ethyl-2-thio-2,4-oxazolidinedione (ITO-1), and 5-benzilidene-3-ethyl rhodanine (BTR-1), and have tested their chemotherapeutic properties. that all three compounds induced cytotoxicity in a time-and concentration-dependent manner on leukemic cell line, CEM."
"Among the compounds tested, BTR-1 was 5- to 7-fold more potent than ITH-1 and ITO-1 when compared by trypan blue and MTT assays. IC50 value of BTR-1 was estimated to be <10 mc M. Both cell cycle analysis...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Hematology Week
Source: Hematology Week (2010-11-29)
More Articles from Hematology Week
- Lymphoma
Investigators at Ajou University, Department of Diagnostic Radiology have published new data on lymphoma - T-Cell Lymphoma
Investigators at Oakland University, Department of Nuclear Medicine zero in on t-cell lymphoma - Clinical Chemistry
New findings from Jiangsu University, Department of Hematology describe advances in clinical chemistry - Sickle Cell Anemia
Recent findings from O. Oniyangi and co-authors highlight research in sickle cell anemia - Thromboembolism
Reports from University Hospital highlight recent research in thromboembolism - Angiogenesis
Research conducted at Shandong University, Department of Hematology has updated our knowledge about angiogenesis - More from this issue of Hematology Week
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
