Hemodynamics
Study Results from R. Acuna and Colleagues Broaden Understanding of Hemodynamics
Published in Hematology Week, May 9th, 2011
2011 MAY 9 -- According to recent research from Mexico City, Mexico, "Screening for variants in SLC12A1 and SLC12A3 genes, encoding the renal Na+:Cl- (NCC) and Na+:K+:2Cl(-) (NKCC2) cotransporters, respectively, in 3125 members of the Framingham Heart Study (FHS) revealed that carrying a rare mutation in one of these genes was associated with a significant reduction in blood pressure, in the risk of arterial hypertension, and of death due to cardiovascular disease. Because near 60% of the rare mutations identified have not been related to Bartter's or Gitelman's disease, the consequence of such mutations on cotransporter activity is unknown."
"We used the...
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Source: Hematology Week (2011-05-09)
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