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Enzyme Precursors

New Enzyme Precursors Study Results from University of Texas Described

Published in Hematology Week, September 5th, 2011

2011 SEP 5 -- According to the authors of a study from Houston, Texas, "Microbubbles (MB) combined with ultrasound (US) have been shown to lyse clots without tissue-type plasminogen activator (tPA) both in vitro and in vivo. We evaluated sonothrombolysis with 3 types of MB using a rabbit embolic stroke model."

"New Zealand White rabbits (n=74) received internal carotid angiographic embolization of single 3-day-old cylindrical clots (0.6x4.0 mm). Groups included: (1) control (n=11) embolized without treatment; (2) tPA (n=20); (3) tPA+US (n=10); (4) perflutren lipid MB+US (n=16); (5) albumin 3 mu m MB+US (n=8); and (6) tagged albumin 3 mu m MB+US (n=9)....

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