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HBV/Vaccine - Post-Vaccination Complication

"Acute Posterior Multifocal Placoid Pigment Epitheliopathy after Hepatitis B Vaccine."

Published in Hepatitis Weekly, April 24th, 1995

According to the authors' abstract of an article published in Archives of Ophthalmology, "Objective: To report two cases of acute posterior multifocal placoid pigment epitheliopathy after immunization with a recombinant hepatitis B virus vaccine. Design: Case reports. Results: Two patients had development of visual loss 3 days to 2 weeks after the booster administration of 20 (mu)g of recombinant hepatitis B virus surface antigen (Engerix-B). In both cases, fundus examination, fluorescein angiograms, and the course of the disease were typical of acute posterior multifocal placoid pigment epitheliopathy. In case 1, 1 week after immunization, the leukocyte...

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