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Therapy - Interferon Alpha

"Prediction of Sustained Response to Interferon Alpha Therapy with Serum Soluble Interleukin 2 Receptor Levels in Patients with Chronic Hepatitis C."

Published in Hepatitis Weekly, May 1st, 1995

According to the authors' abstract of an article published in International Hepatology Communications, "It is difficult to predict sustained response to interferon alpha therapy for patients with chronic hepatitis C. Loss of serum hepatitis C viral RNA (HCV-RNA) and normal serum alanine aminotransferase (ALT) level at the end of treatment do not necessarily mean sustained response. Relapses are very common. In this study, serum levels of soluble interleukin 2 receptor (sIL-2R, an indicator of immune response) were investigated to see if they are helpful to predict sustained response. We studied consecutive twenty patients with chronic hepatitis C who had HCV-RNA negativity and normal...

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