Blood Banking/Viral Inactivation

Nucleic Acid May Be Key Target for Photoinactivation

Published in Hepatitis Weekly, May 29th, 1995

Nucleic acid may be an important target for photoinactivation of certain viruses in blood, Red Cross researchers suggested.

Numerous groups have attempted to inactivate viruses in blood products through the use of photoactive compounds and irradiation with UV or visible light, noted Hideki Abe, Hokkaido Red Cross Blood Center, Sapporo, Japan, and Stephen J. Wagner, the Jerome H. Holland Laboratory for the Biomedical Sciences, American Red Cross Blood Services, Rockville, Maryland.

Viral transmission from blood transfusion occurs infrequently, in spite of improved donor screening and testing for infectious agents, noted Abe and Wagner. In Japan, some...

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Source: Hepatitis Weekly (1995-05-29)

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