Virology

Precore Mutants Prevail over Wild-Type HBV in HBeAg-Negative Carriers

Published in Hepatitis Weekly, May 29th, 1995

Researchers from Japan suggested that in all hepatitis B e antigen (HBeAg)-negative hepatitis B virus (HBV) carriers, precore mutants prevail over wild-type HBV within several years following seroconversion.

Tatsunobu Karasawa, Jikei University School of Medicine, Tokyo, Japan, and colleagues performed a study to clarify the relationship between the clinical severity of chronic liver disease and the precore mutations in HBeAg-negative HBV carriers ("Genetic Heterogeneity in the Precore Region of Hepatitis B Virus in Hepatitis B e Antigen-Negative Chronic Hepatitis B Patients: Spontaneous Seroconversion and Interferon-Induced Seroconversion," Journal of Medical...

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Source: Hepatitis Weekly (1995-05-29)

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