"Loss of Serum HCV RNA at Week 4 of Interferon-Alpha Therapy is Associated with More Favorable Long-Term Response in Patients with Chronic Hepatitis C."

According to the authors' abstract of an article published in Journal of Medical Virology, "To determine the virological factors associated with a favorable long-term response to interferon-alpha (IFN) therapy in chronic hepatitis C virus (HCV) infection, 61 Japanese patients with chronic HCV infection were treated with IFN for 24 weeks (780 million units in total) and followed for 8 to 16 months after cessation of therapy. Ten patients dropped out because of severe side effects. Of the 51 patients who completed IFN therapy, 23 showed complete and sustained response (CR-->SR), 13 complete response with early relapse (CR-->Rel), and 15 no response to IFN (NR). For the pretreatment...

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