HBV Gene Expression
"Effects of Ethanol on Hepatitis B Virus Pre-S/S Gene Expression in the Human Hepatocellular Carcinoma Derived HEP G2 Hepatitis B DNA Positive Cell Line."
Published in Hepatitis Weekly, September 18th, 1995
According to the authors' abstract of an article published in Journal of Hepatology, "Background/Aims: Among the reported interactions between ethanol and hepatitis B virus (HBV), studies of transgenic mice have suggested an effect of ethanol on the secretion of viral envelope proteins. Methods: We further investigated these interactions in vitro by determining HBs antigen levels and performing northern blots of viral mRNA in human cell culture (HepG2 HBV positive cells) exposed for 3 to 12 days to various concentrations of ethanol. Results: In cultures exposed to 200 mM ethanol, HBs antigen concentrations increased in the medium (P<0.05) after 3 days...
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Source: Hepatitis Weekly (1995-09-18)
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