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Diagnostics (HCV)

"Rapid Genotyping of Hepatitis C Virus RNA-Isolates Obtained from Patients Residing in Western Europe."

Published in Hepatitis Weekly, October 9th, 1995

According to the authors' abstract of an article published in Journal of Medical Virology, "Two rapid genotyping methods for hepatitis C virus (HCV), the line probe assay (Inno-LiPA) and the subtype-specific core amplification system [Okamoto et al., (1992b) Journal of General Virology 73:673-679], were applied to 58 HCV isolates which were typed as type 1 (n=37) acid type 2 (n=21) by sequence analysis of the 5' untranslated region (5'UTR). The line probe assay targets the 5'UTR and recognized 12 subtype 1a, 25 subtype 1b, 18 subtype 2a, 2 subtype 2b and 1 subtype 2d in accordance with sequence analysis of this region. Subtype-specific core amplification revealed 7 discrepancies among...

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