Autoimmune Hepatitis (Therapy)

Remission Is Maintained with High Dose of Azathioprine Alone

Published in Hepatitis Weekly, October 30th, 1995

A high dose of azathioprine is effective in keeping certain patients with autoimmune hepatitis in remission.

While prednisolone, usually combined with azathioprine, is effective in maintaining remission in the majority of autoimmune hepatitis patients, most such patients experience relapse when treatment stops and need long-term therapy, noted Philip J. Johnson, M.D., and colleagues, King's College Hospital and School of Medicine and Dentistry, London, United Kingdom. However, extended corticosteroid therapy can have toxic effects.

In 1984 Johnson et al. conducted a controlled trial to study the effectiveness of maintenance therapy with azathioprine...

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Source: Hepatitis Weekly (1995-10-30)

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