Hemophilia

HCV-1 Associated with Poor INF Response in Hemophiliacs

Published in Hepatitis Weekly, February 5th, 1996

Hepatitis C virus type 1 infection may be associated with more severe symptoms and poor response to interferon therapy in hemophilic patients, according to a report from Great Britain.

Chronic hepatitis C virus (HCV) infection is highly prevalent in hemophilic patients treated in the past with non-virally inactivated clotting factor concentrates. While the long-term consequences of this infection are not yet known, information available from non-hemophilic patients indicates that a substantial proportion will progress to cirrhosis over the course of two or more decades, with the clinical sequelae of hepatic decompensation, variceal bleeding, and hepatocellular...

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Source: Hepatitis Weekly (1996-02-05)

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